Senior Director, Health Economics and Outcomes Research / Real World Evidence

Company: IDEAYA Biosciences
Location: South San Francisco
Posted on: January 27, 2026

Job Description:

Non-Solicitation Policy and Notice to Agencies and Recruiters: IDEAYA's Non-Solicitation Policy strictly prohibits agencies and recruiters from any contact and communication with IDEAYA employees, managers, and leaders to submit unsolicited candidate resumes and/or to solicit business partnerships . Submission of unsolicited candidate resumes by agencies or recruiters with or without a contract in place with IDEAYA Biosciences Inc. will not create any implied obligation. Failure to comply with this policy will result in disqualification from current and future business opportunities with IDEAYA Biosciences. All recruiting and talent agency decisions are strictly managed by the internal IDEAYA Human Resources function. All communication by external agencies and recruiters must be directed to humanresources@ideayabio.com. We ask that you only email your interest once. Job Summary About IDEAYA Biosciences: IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small-molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first-in-class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody-drug conjugates, or ADCs, for molecularly defined solid tumor indications. Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer. When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use teamwork to move science forward. For more information, please see www.ideayabio.com. Location: South San Francisco, CA. Position Summary: We are seeking a Senior Director of Health Economics and Outcomes Research / Real World Evidence (HEOR/RWE) to join the IDEAYA Commercial team. The Senior Director, HEOR/RWE will be responsible for shaping and executing IDEAYA’s health economics, outcomes research, and real-world evidence strategy for the launch of darovasertib in metastatic uveal melanoma (mUM). This leader will play a pivotal role in generating evidence in a very high unmet disease area for payers, providers, and patients. They will have an opportunity to take innovative approaches to value demonstration in orphan diseases, biomarker-driven populations, and unique combination treatments. While the initial focus will be on darovasertib, this role will evolve over time to include direct reports and contribute on the global launches of IDEAYA’s exciting pipeline of oncology assets. This position is based in our South San Francisco headquarter offices and required to be onsite four days per week per our company policy. Reporting to: Vice President, Value and Access Job Description What you’ll do: Develop and execute the HEOR and RWE strategy to support US value demonstration for darovasertib at launch and through its lifecycle Collaborate with Market Access, Medical Affairs and Clinical Development to evaluate data gaps and develop robust evidence generation and publication plans Develop and execute core evidence-generation activities including chart reviews, literature reviews, PRO studies, and micro-costing analyses to strengthen the clinical and economic differentiation of the product Design and implement real-world data analyses to articulate the current patient demographics, treatment patterns, and outcomes for mUM patients Develop comprehensive health economic model analyses to demonstrate value, inform pricing strategy, and support reimbursement decisions Partner with Market Access to develop robust and compelling clinical, humanistic, and economic value propositions and oversee development of AMCP and Global Value Dossiers Lead the external dissemination of HEOR/RWE deliverables including publications, presentations, and professional conferences Develop, train, and implement the resources that support field HEOR efforts with key customers; ensure programs and materials comply with SOPs and Medical, Legal & Regulatory (MLR) reviews Engage and collaborate with external partners including payers, providers, and other access decision-makers to establish / maintain strong partnerships and gather insights Support field team engagements during Preapproval Information Exchange (PIE) and post-approval interactions to educate payers and provider access stakeholders on darovasertib Stay current with advancements in methodologies and best practices; Closely monitor new trends in health policy and payer environment and integrate into cross-functional strategies Influence the design of IDEAYA’s clinical development programs through global price and market access and commercial opportunity assessments Oversee budgeting and financial planning for all HEOR/RWE activities Requirements: Advanced, doctoral level degree in related discipline with at least 10-15 years of related experience Experience in Biotech/Pharmaceutical industry in US HEOR/RWE and with market access strategies Experience with rare disease and oral drugs is strongly preferred Demonstrated success with US commercialization and launches Deep technical knowledge and experience with Clinical and HEOR / RWE data sets, methodologies, analyses, and processes to optimize execution of value evidence tactics Experience developing US and global value evidence generation plans for pipeline assets Experience establishing relationships with clinical and HEOR experts Experience interacting with US access decision-makers Excellent communication and presentation skills, ability to present to diverse stakeholders including external partners, healthcare professionals and senior leaders Excellent organizational, project management and problem-solving skills Ability to thrive in a fast-evolving environment In-office role (4x per week) with 15% estimated travel to vendor partners and relevant conferences/meetings as deemed necessary All employees are expected to act with integrity and in full compliance with applicable laws, regulations, and IDEAYA policies, including IDEAYA’s Code of Conduct.Employees must demonstrate good judgement and ethical behavior in all business activities, maintain patient and product safety as a top priority, and report any suspected violations of law or Company policy through appropriate channels Total Rewards Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval). Our comprehensive benefits package includes, but is not limited to, medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), 401k, ESPP, and wellness programs. The expected salary range for the roleof Senior Director, Health Economics and Outcomes Research / Real World Evidence is $282,000-349,000. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the office location where this open position is located, the final candidates’ experience within their profession, experience in the disease areas we are striving to make an impact in as a company, length of time within the industry, educational background, and performance during the interview process. The Company complies with all laws respecting equal employment opportunities and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite in the office at the Company’s facilities for training & meetings, with work-from-home flexibility, and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization. IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.

Keywords: IDEAYA Biosciences, San Leandro , Senior Director, Health Economics and Outcomes Research / Real World Evidence, Science, Research & Development , South San Francisco, California